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OLYMPUS PLATFORM

OLYMPUS

PLATFORM

A dynamic, turnkey, automated, infrastructure solution operating at a peta-byte scale; completely eliminating the need to build or integrate multiple solutions to process, analyze, interpret and store genomic data; with security, scalability and regulatory compliance to meet organizational standards.

INTELLIGENT BIOINFORMATICS
INTELLIGENT INFRASTRUCTURE
COMPLIANCE & SECURITY

Powerful Platform &

Intelligent Architecture

On Demand Compute & Storage; Unparalleled  Security & Compliance

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Dynamic, peta-byte scale, compute infrastructure platform delivering a holistic environment to manage all your genomic analytical requirements  and bioinformatics data in one secure location. 

Fully Automated, Turn-Key

NGS Genomic Data Analytics

DNA Germline, RNA-seq, CNV,

Tumor / Normal (Somatic), SV,

Custom Pipelines

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Optimize bioinformatics workflows with full automation from sequencer to results, with fastest performance delivering highest accuracy, eliminating costly bioinformatics investments and significantly reducing false discoveries.

End-to-End Integration with NGS Lab

LIMS

EHR/EMR

Third Party Tools

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Logical integration with complementary information management solutions, facilitating enhanced capability to automate & streamline results eliminating the need for human intervention.

Discovery Analytics &

Genomic Association Studies

Multivariate Discovery

Analytics and Genome

Association Studies

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A powerful, scalable solution ideal for population analytics, leveraging proprietary tools & integrated content, enabling genomic association studies, pairwise & multivariate analytics & outcomes analyses delivering actionable results in minutes.

Bioinformatics

GenomeNext’s proprietary Olympus Platform is specifically designed to comprehensively integrate with your organizational NGS workflows delivering a true end-to-end, automated, genomic sequence analysis solution to manage and interpret genomic data, requiring no bioinformatics investment, hardware acquisition and installation, or software development. The Olympus Platform provides a continuous workflow and data management solution from the sequencing instrument through analysis, annotation, reporting, and interpretation, including a proprietary solution for multivariate discovery analytics and genetic association studies.

INTELLIGENT

BIOINFORMATICS

FULLY AUTOMATED NGS PIPELINES:

Germline, Tumor/Normal (Somatic), Copy Number Variants (CNV), Structural Variants (SV), RNA & Custom

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Automated Data Streaming from NGS Instrument to OLYMPUS

Raw Data Conversion & QC

Sample Validation:

Inheritance & Concordance Checks

Genomic Analysis:

  • DNA

  • RNA

  • Cancer

  • CNV

  • SV

  • Custom Pipeline

Results QC

OLYMPUS - Genomic Analysis & Data Management

Genomic Visualization

HELIOS

Annotation & Interpretation

ATHENA

Predictive Analytics & ACMG Reporting

EHR / LIMS Integration   |   CAP/CLIA & Regulatory Compliance   |  24x7 Security   |    Unlimited Data Storage

CLINICALLY ACTIONABLE RESULTS
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Sensitivity

(True Positives)

99.76 %
99.99 %

Specificity

(True Negatives)

99.99 %

Diagnostic Effectiveness

(Diagnostic Index = Specificity + Sensitivity -1)

ACCURATE - REPRODUCIBLE - DETERMINISTIC

CRITICAL FOR

CLINICAL DIAGNOSIS

 

IS YOUR SOLUTION TRULY

REPRODUCIBLE &

DETERMINISTIC?

GenomeNext’s proprietary technology enables NO DOWNSAMPLING and does not discard any sequence reads, therefore analysis results are exactly identical each and every run.

NO OTHER PIPELINE/COMPETITOR CAN DELIVER 100% REPRODUCIBLITY

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Given a set of raw sequence data as input, every execution of the program produces identical variant calls and genotypes as the final output and regardless of the scale of parallelization, the final result is identical.

NO OTHER PIPELINE/COMPETITOR CAN DELIVER 100% DETERMINISM

PERFORMANCE

Whole
Genome
Analysis

30-50X Whole Genome ranging between 85GB-110GB will analyze in under 2.5 hours.

Whole
Exome
Analysis

50-100X Exome

ranging between 6-15GB

will analyze in under 1.5 hours.

Targetted
Panel
Analysis

100x Targetted Panel

ranging between 1GB – 5GB will analyze in under 30 minutes.

Infrastructure

INTELLIGENT INFRASTRUCTURE

PLATFORM

Holistic / Integrated Environment

  • Genomic Analysis

  • Data Management

 

No Bioinformatic Investment

  • Immediate On-Boarding

  • Seamless Workflow

  • No Architecture or Engineering

  • No Bioinformatic Intervention

  • Reduces Overhead and Monitoring

 

Regulatory Compliant

  • CLIA, CAP, HIPAA, ISO 27001

  • Clinically Validated

 

Market Leading Security

  • FISMA Moderate

  • Security Operations Center

  • 24x7 Monitoring

  • Log/Threat Management

 

Enterprise Data Management

  • Data Sharing / Collaboration

  • Organizational Analytics

  • Unlimited Storage Capacity

DATA MANAGEMENT

& AUTOMATION

GenomeNext Automation Significantly Reduces Time, Cost & Operational Burden

  • Seamless integration with Sequencer

  • Automated streaming from sequencer to Olympus

  • Automated demultiplexing & conversion

  • Auto analysis generation

  • No bioinformatic or manual intervention

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SECURE GENOMIC DATA STORAGE

Free Data Storage

  • You control your data from any device. Access your data anywhere in the world quickly and securely using our cloud based platform on any device.

  • No limit to the storage capacity of our solution, store as much data as you need and access it anytime.

  • Run population scale genomics with no need to worry about storage capacity, security or cost.

Genomic Data Upload

Upload large data files directly to your account for analysis and storage using your web browser. If you are unable to utilize your network bandwidth to upload large data files, please contact us so we can provide you with a secure, custom upload solution that is right for you.

HEALTH SYSTEM INTEGRATION

GenomeNext seamlessly integrates with clinical health systems, offering full service solutions to customize intelligent bioinformatics workflows for patient care. With the ability to integrate with EMR/EHR, LIMS, and Reporting Systems streaming directly from the sequencing instrument, our solutions save time, money, and eliminate the need for human intervention, eliminating error and overhead.

CUSTOM PIPELINE INTEGRATION

GenomeNext will work with you to integrate your home-grown, custom -omics pipelines into our fully automated Olympus Platform. Simply provide us with your requirements and our full service bioinformatics team will provide you with a fully automated –omics analysis pipeline with all the benefits and features that are part of our Olympus Platform.

CUSTOM DEPLOYMENT MODELS

GenomeNext Olympus Platform is a turn-key, fully automated solution that provides you instant access to the most accurate and reproducible genomic analysis tools available. We do understand that different organizations have specific requirements when it comes to managing their own data, thus, the Olympus Platform can be deployed to meet customer's various differnt business requirements. In addition to the deployments listed below, the GenomeNext solution can be deployed as a hybrid solution, leveraging your on-premise resources with the power of the Cloud to proivde you with optimal results based on your requirements. 

 

With all of our deployment options, the GenomeNext Olympus Platform provides CAP and CLIA compliant processes and maintains HIPPA standards for security and privacy protection.

GenomeNext
SaaS Solution

Fully managed cloud solution that provides complete automation from sample creation to analysis results. 

 

Turn-key, fully automated.

 

No bioinformatics intervention needed.

 

Data securely stored in our Cloud platform.

 

Analysis results in:

3 hours for whole genome

90 minutes for exome

30 minutes for panel

Private Cloud
Managed by US

Private GenomeNext solution deployed in isolated, private Cloud network and fully managed by the GenomeNext team.

 

 Provides complete automation from sample creation to analysis results. 

 

No bioinformatics intervention needed.

 

Data securely stored in private Cloud network.

 

Analysis results in:

3 hours for whole genome

90 minutes for exome

30 minutes for panel

Private Cloud
Managed by YOU

Private GenomeNext solution deployed in your private Cloud account and fully managed by your team.

 

 Provides complete automation from sample creation to analysis results. 

 

No bioinformatics intervention needed.

 

Data securely stored in your private Cloud network.

 

Time for analysis results will depend on quantity of computational resources available.

On Premise, Local Solution

GenomeNext's secondary analysis solution (FASTQ to VCF) is privately deployed  locally within your datacenter.

 

Bioinformatics intervention required.

 

Data securely stored in your local datacenter.

 

Time for analysis results will depend on quantity of computational resources available.

Hybrid
Solution

Custom hybrid solutioin that allows you to leverage the power of the Cloud while utilizing your local infrastructure to meet your organization's requirements.

 

The GenomeNext solution deployed on the Cloud (private or managed by GenomeNext) to quickly analyze samples while utilizing your local datacenter to run local applications.

Compliance

Security

Compliance Security

COMPLIANCE

GenomeNext maintains a strong commitment to protect not only the privacy and security of our customer’s data but also to promote and support our customer’s compliance requirements.  Should you have any questions regarding features, processes and safeguards of the GenomeNext platform and how they apply to your business application(s) please contact us at support@genomenext.com for more additional information.

GenomeNext has employed technical and process controls, including Data Encryption, Data Protection, Version Control, Record Retention, Auditing, Backup and Disaster Recovery to facilitate compliance with federal regulatory agencies for clinical support. GenomeNext implements and executes BAA agreements that may be required for HIPAA compliance.  Please contact us at support@genomenext.com to request a BAA.

HIPAA

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CLIA

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CAP

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ISO27001

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EU-US Privacy Shield

 

GCP/GLP

SECURITY

Cloud Security

Our security environment is designed and managed in alignment with security best practices and a variety of IT security standards, including:

 

  • SOC 1/SSAE 16/ISAE 340

  • SOC 2 / SOC 3

  • ISO 27001

  • PCI DSS Level 1

  • FedRamp, FISMA, and DIACAP

  • ISO 9001

  • DOD CSM level 1-5

  • MTCS level 3

Cloud Security Standards

The Olympus Platform is configured for least privileged communication, administration, and access, as well as continuous security monitoring and auditing of the overall platform (Infrastructure, Applications, Network, and Data).  Security controls include:

 

  • 24×7 security operations center

  • Active auditing of logs, intrusion detection/prevention, penetration testing, and web application firewalls

  • Two-factor authentication access. 

  • Log management, threat management, and web security management

  • Encryption of data in transit and at rest with 256-bit Advanced Encryption Standard (AES-256)

  • Failover and Disaster Recovery

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